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Figure 3 | Molecular Cancer

Figure 3

From: p14ARF induces the relocation of HDM2 and p53 to extranucleolar sites that are targeted by PML bodies and proteasomes

Figure 3

PML bodies are randomly scattered in nuclei where pBabe-p14ARF exclusively localized to nucleoli (top row) but gradually associate with the p14ARF positive extranucleolar inclusions in parallel with their expansion (2nd–5th raw) in MCF7 cells. p14ARF positive nuclear inclusions are denoted by hollow arrowheads and nucleoli by full arrowheads. Green – p14ARF, red – PML protein, blue – DNA-staining.

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