Figure 2From: SLC/CCL21-mediated anti-tumor responses require IFNγ, MIG/CXCL9 and IP-10/CXCL10SLC/CCL21-treated mice had a significant induction in IFNγ, MIG/CXCL9 and IP-10/CXCL10 at the tumor site compared to diluent treated control tumor bearing mice (p < 0.001). Assessment of cytokine production at the tumor site of SLC/CCL21 treated mice receiving anti-IFNγ, anti MIG/CXCL9 and anti IP-10/CXCL10 showed an interdependence of IFNγ, MIG/CXCL9 and IP-10/CXCL10: neutralization of any one of these cytokines in vivo caused a concomitant decrease in all three cytokines (*p < 0.01 compared to the control antibody treated group). Results are expressed as pg/mg of total protein. Total protein was determined by the Bradford assay. n= 8 mice per groupBack to article page