Table I Endothelial cell genes (ECG) detected by SSHDD. BLAST searches revealed similarity to the accession # provided on the right most column. Genbank accession number in bold letter denotes complete cDNA sequence deposited by the authors.

Known Genes associated with the activation of endothelial cells

Matrix metalloproteinases-1 (MMP-1)

X54925

3,25,26

Matrix metalloproteinases-2 (MMP2)

NM_ 004530

3,25,26

Stromelysin (MMP-3)

X05232

2,3,25

Type IV collagenase (MMP9)

J05070

2,3,26

Myeloblastin

M75154

25,26

Cathepsin B

M14221

28

Calpastatin

E02261

29

Urokinase plasminogen activator surface receptor (uPAR)

X51675

2,30

Vascular endothelial growth factor receptor (VEGFR1/FLT-1)

AF063657

4,5

Vascular endothelial growth factor receptor-2(VEGFR-2/KDR)

X61656

4,5,6

Vascular cell adhesion molecule-1 (VCAM-1)

X53051

2,3

α₂ integrin subunit

X17033

2,20

VE-cadherin

X79981

2,3,21

Prostaglandin endoperoxidase (Cox)

E03346

2,32

Metabolic and miscellaneous genes

Ketohexokinase

P50053

-

Adenosine deaminase

X02994

-

Spermidine synthase

M64231

-

Adenylyl cyclase

X74210

33

Platelet factor 4 (PF4)

M25897

34

Stanniocalcin

U25997

35,36

Candidate genes associated with the activation of endothelial cells

Clone 7D Kinesin-heavy chain (KHC)

X65873

37

Clone 17E Epiregulin (Epireg)

NM_001432

38

Clone 22G Similar to transcription factor BTF3

XM_038290

40

Clone 33A Phosphatidic acid phosphatase-2b (PAP2b/VCIP)

AB000889/AF480883

40,41

Clone 37F Synaptojanin-2 (similar to KIAA0348 protein)

AB002346

42,43

Clone 48A Similar to GPCR kinase-interactor-2 (GIT-2)

NM_014776

44

Clone 54C Smg GDS-associated protein (SMAP)

AI401257/U59919

45

Clone 77D Angiopoietin related protein (AngRP)

AF169312

46

Clone 94H Similar to Ribosomal protein L19 (RibL19)

AB019566/BC013016

47,48

Clone 263F Eukaryotic translation EF-1 alpha l(EF-lal)

BC028674

49

Clone 309C Stabilin-1

NM_015136

50