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Figure 4 | Molecular Cancer

Figure 4

From: The Biology of the Ets1 Proto-Oncogene

Figure 4

Ternary complexes of Ets1 with AML1, Pit-1 or Pax5 and DNA. TAD = transactivation domain, NRDB = negative regulatory domain for DNA binding (autoinhibitory domain of AML1), runt = DNA binding domain of AML1, POU-HD = POU homeo domain (C-terminal DNA binding domain of Pit-1), POU-S = POU-specific (N-terminal DNA binding domain of Pit-1), CTD = C-terminal DNA binding domain of Pax5, NTD = N-terminal DNA binding domain.

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