Figure 2
From: Effects of STI571 (gleevec) on pancreatic cancer cell growth
FACS analysis, Annexin-V and PI staining. Mia-PaCa-2 and T3M4 cell lines were cultured in complete medium overnight, and treated with GI50 concentrations of STI571 for 12 and 48 hours. Annexin and PI staining revealed increasing percentages of Annexin-positive and PI-positive cells with increasing time of STI571 incubation. Cell cycle analysis showed no changes in cell cycle distribution and no apoptosis (lower panel). The figure is representative of three independent experiments.