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Table 1 Serum Gal/GalNAc estimation by PNA/ELLA in ESCC (Upper limit of normal = 0.159 A450)

From: Expression of peanut agglutinin-binding mucin-type glycoprotein in human esophageal squamous cell carcinoma as a marker

Parameters

Group

No. Patients

Mean O.D ± S.D.

Gal/GalNAc

I Normal

50

0.071 ± 0.044

 

II WDESCC

18

0.349 ± 0.131*

 

MDESCC

50

0.402 ± 0.169*

 

PDESCC

32

0.392 ± 0.171*

 

III WDESCC

11

0.319 ± 0.142*

 

MDESCC

47

0.411 ± 0.119*

 

PDESCC

25

0.319 ± 0.149*

  1. Gal/GalNAc – Galactose β-1, 3-α, N-acetyl galactosamine PNA/ELLA – Peanut Agglutinin/Enzyme Linked Lectin Assay ESCC – Esophageal Squamous Cell Carcinoma OD – Optical Density Group I – Healthy volunteers Group II – Before therapy WDESCC – Well Differentiated Esophageal Squamous Cell Carcinoma MDESCC – Moderately Differentiated Esophageal Squamous Cell Carcinoma PDESCC – Poorly Differentiated Esophageal Squamous Cell Carcinoma Group III – After therapy * (P < 0.05) Significant of group II and III against group I
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Molecular Cancer

ISSN: 1476-4598