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Table 1 Examples of Angiogenic Growth Factors that Are Overexpressed in Human Pancreatic Cancer and their Cognate Receptors

From: Pathways for aberrant angiogenesis in pancreatic cancer

Growth Factors Activating Tyrosine Kinase Receptors Receptor
VEGF-A VEGFR-1 and VEGFR-2
VEGF-C VEGFR-3
EGF, TGF-α, HB-EGF EGF receptor
FGF-1, -2, -5 FGF receptors, types 1 and 2
PDGF B chain PDGF receptors α and β
IGF-1 IGF-1 receptor
Hepatocyte growth factor MET
Growth Factors that Activate Serine-Threonine Kinase Receptors  
TGF-β1, -2, -3 Type II TGF-β receptor
Pro-Angiogenic Chemokines  
IL-8 CXCR1 and CXCR2
Mip 3α CCR6