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Figure 6 | Molecular Cancer

Figure 6

From: Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer

Figure 6

mCRBP hypermethylation and silencing is an oncogene-specific event. A. Northern blot analysis. B. mCRBP bisulfite sequencing results for the cell lines tested in A. Each row corresponds to one sequenced amplicon. Filled circles designate methylated and open circles designate unmethylated CpGs (ee legend to Fig. 2B for futher details). C. RT-PCR demonstrating effect of azaC treatment (as in Fig. 4) on mCRBP expression in 16MB9a cells.

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