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Figure 1 | Molecular Cancer

Figure 1

From: Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells

Figure 1

mtDNA copy number and proteins in M010b cells. A, mtDNA copy number in GBM cell lines (M010b, M059K, M006x, M006xLo) and a normal fibroblast cell strain (GM38) by quantitative PCR. Graphical analyses of cytochrome b (■) and β-actin (▼) amplified from serially diluted template DNA. Standard curves were derived from three or more independent PCR experiments. Error bars show mean ± s.d. B, 35S-labeled mitochondrial translation products in M010b cells. The ND6 protein (indicated by the arrow) was identified on the basis of its relative position within the electrophoretic migration pattern of the 13 mtDNA-encoded proteins [25].

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Molecular Cancer

ISSN: 1476-4598