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Figure 6 | Molecular Cancer

Figure 6

From: RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells

Figure 6

Effects of co-cultivated mouse tumor cells on gene expression profile of mouse endothelial cells. PY4.1 cells expressing Flag-PABP and 4T1 cells were grown either separately or together in a co-culture. Cell extracts from the co-culture and from a mixture of the monocultures were prepared. Immunoprecipitation of extracts with anti-Flag antibodies generated two distinct PY4.1 cells mRNA populations that were compared by microarray. The comparison revealed PY4.1 cellular genes that changed their gene expression profile in response to presence of 4T1 breast cancer cells.

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Molecular Cancer

ISSN: 1476-4598