Table 4 Co-ordinately expressed genes sharing chromosomal location
From: Gene expression profiling of epithelial ovarian tumours correlated with malignant potential
Gene Symbol | Location | Expression in cancer | Function |
|---|---|---|---|
KIF2C | 1p34.1 | Up | Nuclear division/mitosis |
CDC20 | 1p34.1 | Up | Regulation of cell growth |
PMSB2 | 1p34.2 | Up | Protein Catabolism |
UBE2C | 20q13.12 | Up | Nuclear division/mitosis |
STK6 | 20q13.2-q13 | Up | Signal Transduction |
RGS19 | 20q13.3 | Up | Nuclear division/mitosis |
PDGFRA | 4q11-q13 | Down | Regulation of cell growth |
IGFBP7 | 4q12 | Down | Regulation of cell growth |
HNRPDL | 4q13-21 | Down | RNA binding |
FYN | 6q21 | Down | Calcium ion transport |
LAMA2 | 6q22-q23 | Down | Cell adhesion |
CTGF | 6q23.1 | Down | Cell adhesion |
FOXM1 | 12p13 | Up | Transcriptional regulation |
CCND2 | 12p13 | Down | Nuclear division/mitosis |
ERBB3 | 12p13 | Up | Signal Transduction |