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Table 1 Promoter methylation of colon cancer cell lines. MSI, microsatellite instable; MSS, microsatellite stable; U, unmethylated; M, methylated. The references give results in agreement with our own data except when the reference is underlined. Note that reference 15 does not use the category monoallelic methyaltion, but reports the promoters only as methylated or unmethylated.

From: A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

 

Cell line

hMLH1

MGMT

p16 INK4a

p14 ARF

APC

E-Cadherin

MSI

       
 

Co115

M12

M

M12

M

U/M

U

 

HCT15

U12,13,14,15

U/M15,16

M12,14,15

M14,15,17

U

U15

 

HCT116

U12,13,15,18,19,20,21,22

U/M15,20

U/M12,15,20,21,22,23

U/M15,17,21,24

U/M

U15

 

LoVo

U12,13,14,15,18,22,26

U15,31

M12,14,15,22

M14,15,24,25

U

U15

 

LS174T

U12,13,18,22

U/M

U12,22

U/M

U

U

 

RKO

M15,18,19,20,22,26

U15,20

M15,20,22,27

M15,24

U

M15

 

SW48

M12,13,14,15,18,20,22,26,28,29

M15,20,31

M12,14,15,20,22,27,29

M14,15,24

U

U15

 

TC7

U12

U

U12

U/M

U

U

 

TC71

U12

U

M12

U

U

U/M

MSS

       
 

ALA

U12

U

M12

U

M

U

 

Colo320

U12,14,18,30

M

M12,14,27

U14

U30

M

 

EB

U12

M

M12

U

U

U

 

FRI

U12

U/M

U12

U/M

U

U

 

HT29

U12,13,14,15,18,21,22,26,30

U15,31,32,33

M12,14,15,21,22,27

U14,15,21,24

U30

U15

 

IS1

U12,21

U

M12,21

M21

U

U

 

IS2

U12

U

U/M12

M

U

U

 

IS3

U12

U

U12

M

U

U

 

LS1034

U12,13

U/M

U/M12

M

U/M

U

 

SW480

U12,14,15,19,21,22,26,30

U/M15

M12,14,15,21,22,27

U14,15,21,24,25

U30

U15

 

V9P

U12

U

U12

U

U

U

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Molecular Cancer

ISSN: 1476-4598