Skip to main content

Table 1 Promoter methylation of colon cancer cell lines. MSI, microsatellite instable; MSS, microsatellite stable; U, unmethylated; M, methylated. The references give results in agreement with our own data except when the reference is underlined. Note that reference 15 does not use the category monoallelic methyaltion, but reports the promoters only as methylated or unmethylated.

From: A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines

  Cell line hMLH1 MGMT p16 INK4a p14 ARF APC E-Cadherin
MSI        
  Co115 M12 M M12 M U/M U
  HCT15 U12,13,14,15 U/M15,16 M12,14,15 M14,15,17 U U15
  HCT116 U12,13,15,18,19,20,21,22 U/M15,20 U/M12,15,20,21,22,23 U/M15,17,21,24 U/M U15
  LoVo U12,13,14,15,18,22,26 U15,31 M12,14,15,22 M14,15,24,25 U U15
  LS174T U12,13,18,22 U/M U12,22 U/M U U
  RKO M15,18,19,20,22,26 U15,20 M15,20,22,27 M15,24 U M15
  SW48 M12,13,14,15,18,20,22,26,28,29 M15,20,31 M12,14,15,20,22,27,29 M14,15,24 U U15
  TC7 U12 U U12 U/M U U
  TC71 U12 U M12 U U U/M
MSS        
  ALA U12 U M12 U M U
  Colo320 U12,14,18,30 M M12,14,27 U14 U30 M
  EB U12 M M12 U U U
  FRI U12 U/M U12 U/M U U
  HT29 U12,13,14,15,18,21,22,26,30 U15,31,32,33 M12,14,15,21,22,27 U14,15,21,24 U30 U15
  IS1 U12,21 U M12,21 M21 U U
  IS2 U12 U U/M12 M U U
  IS3 U12 U U12 M U U
  LS1034 U12,13 U/M U/M12 M U/M U
  SW480 U12,14,15,19,21,22,26,30 U/M15 M12,14,15,21,22,27 U14,15,21,24,25 U30 U15
  V9P U12 U U12 U U U