Genes
|
Methylation Status
|
Grade classification
|
p-value*
|
p-value†
|
p-value**
|
p-value‡
|
p-value#
|
---|
| |
IA
|
IB
|
IC
| | | | | |
FHIT
|
Methylated
|
3
|
1
|
3
|
1
|
0.0526
|
0.5856
|
0.2352
|
0.041#
|
|
Unmethylated
|
8
|
9
|
1
| | | | | |
FANCF
|
Methylated
|
2
|
1
|
3
|
0.6609
|
0.0312†
|
1
|
0.0769
|
0.041#
|
|
Unmethylated
|
9
|
9
|
1
| | | | | |
Cyclin-D2
|
Methylated
|
0
|
0
|
3
|
0.23
|
0.0017†
|
-
|
0.0088‡
|
0.011#
|
|
Unmethylated
|
11
|
10
|
1
| | | | | |
BRCA2
|
Methylated
|
0
|
0
|
1
|
1
|
0.16
|
-
|
0.2667
|
0.2857
|
|
Unmethylated
|
11
|
10
|
3
| | | | | |
RUNX3
|
Methylated
|
7
|
3
|
4
|
0.6887
|
0.1052
|
0.1984
|
0.5165
|
0.0699
|
|
Unmethylated
|
4
|
7
|
0
| | | | | |
- *Fisher's exact test. IA type vs. IB and IC type; †Fisher's exact test. IA and IB type vs. IC type GCTs of ovarian origin;
- **Fisher's exact test. IA type vs. IB; ‡Fisher's exact test. IA type vs. IC type; #Fisher's exact test. IB type vs. IC type GCTs of ovarian origin