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Figure 3 | Molecular Cancer

Figure 3

From: Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities

Figure 3

Bar graphs indicating percentage of increase of intracellular free [Ca2+] using fura-2. These data were generated from U87MG cells grown in phenol red-free medium for 24 h prior to treatments with the drugs in freshly prepared phenol red-free medium. Four treatment groups: control (CTL); 40 μM dexamethasone (DXM) for 8 h; 100 μM temozolomide (TMZ) for 6 h; pretreatment with 40 μM DXM for 2 h followed by 100 μM TMZ for 6 h. Percent changes in intracellular free [Ca2+] were shown at nM levels. Significant difference between CTL and TMZ treated cells was indicated by * (P ≤ 0.05) and significant difference between TMZ treated cells and DXM plus TMZ treated cells was indicated by # (P ≤ 0.05).

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