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Table 3 List of the 47 target genes selected

From: Identification of a three-gene expression signature of poor-prognosis breast carcinoma

Genesa Genbank accession number Chromosomal location Description
AR NM_000044 Xq11.2-q12 Androgen receptor
AREG NM_001657 4q13-q21 Amphiregulin
ARHC/RhoC NM_175744 1p13.1 Ras homolog gene family, member C
BCL2 NM_000633 18q21.3 B-cell CLL/lymphoma 2
BRCA1 NM_007294 17q21 Breast cancer 1, early onset
BRCA2 NM_000059 13q12.3 Breast cancer 2, early onset
CAV1 NM_001753 7q31.1 Caveolin 1
CCND1 NM_053056 11q13 Cyclin D1
CCNE1 NM_001238 19q12 Cyclin E1
CD44 NM_000610 11p13 CD44 antigen
CDH1 NM_004360 16q22.1 Cadherin 1 (E-cadherin)
CGA NM_000735 6q12-q21 Glycoprotein hormones, alpha polypeptide
CGB NM_000737 19q13.32 Chorionic gonadotropin, beta polypeptide
CP/Ceruloplasmin NM_000096 3q23-q25 Ceruloplasmin
CXCL12 NM_000609 10q11.1 Chemokine (C-X-C motif) ligand 12
CXCR4 NM_003467 2q21 Chemokine (C-X-C motif) receptor 4
DNMT3B NM_006892 20q11.2 DNA (cytosine-5-)-methyltransferase 3 beta
EGFR/ERBB1 NM_005228 7p12 Epidermal growth factor receptor
ERBB2 NM_004448 17q21.1 ErbB2
ERBB3 NM_001982 12q13 ErbB3
ERBB4 NM_005235 2q33.3-q34 ErbB4
ESR1/ERα NM_000125 6q25.1 Estrogen receptor 1 (alpha)
ESR2/ERβ NM_001437 14q Estrogen receptor 2 (beta)
ETV4/PEA3/E1AF NM_001986 17q21 Ets variant gene 4
HAS2 NM-005328 8q24.12 Hyaluronan synthase 2
HMMR/RHAMM NM_012484 5q33.2-qter Hyaluronan-mediated mobility receptor
KRT19 NM_002276 17q21.2 Keratin 19
MKI67 NM_002417 10q25-qter Antigen identified by monoclonal antibody Ki-67
MYC NM_002467 8q24.12-q24.13 c-myc oncogene
p14/ARF NM_058195 9p21 Alternative reading frame p14 (p14ARF)
p15/CDKN2B NM_004936 9p21 Cyclin-dependent kinase inhibitor 2B (p15 CDK inhibitor)
p16/CDKN2A NM_000077 9p21 Cyclin-dependent kinase inhibitor 2A (p16 CDK inhibitor)
PGR/PR NM_000926 11q22-q23 Progesterone receptor
PLAU/UPA NM_002658 10q24 Plasminogen activator, urokinase
PTGS2/COX2 NM_000963 1q25.2-q25.3 Prostaglandin-endoperoxide synthase 2
PTTG1/Securin NM_004219 5q35.1 Pituitary tumor-transforming 1
RB1 NM_000321 13q14.2 Retinoblastoma 1
SERPINB2/PAI2 NM_002575 18q21.3 Plasminogen activator inhibitor type 2
SERPINB5/Maspin NM_002639 18q21.3 Maspin
SERPINE1/PAI1 NM_000602 7q21.3-q22 Plasminogen activator inhibitor type 1
SPP1/Osteopontin NM_000582 4q21-q25 Secreted phosphoprotein 1
SRC NM_005417 20q12-q13 c-src oncogene
TERT NM_003219 5p15.33 Telomerase reverse transcriptase
TFF1/pS2 NM_003225 21q22.3 Trefoil factor 1
TIAM1 NM_003253 21q22.11 T-cell lymphoma invasion and metastasis 1
TOP2A NM_001067 17q21-q22 Topoisomerase (DNA) II alpha 170 kDa
XLKD1/LYVE-1 NM_006691 11p15 Extracellular link domain containing 1
  1. aLocusLink symbol