Cytogentic analysis. Panel A shows an image of fluorescent in situ hybridization. The metaphase chromosome spread is hybridized with two locus specific probes labeled with FITC (green) and SpectrumRed (red). Panel B Spectral karyotype (SKY) analysis of immortalized human prostate epithelial cells. The line was derived from cells previously described . Images provided by Dr. J. Squire.