Table 4 Down-regulated genes in rats fed with SPI diet*

Cell adhesion

   Embigin

AJ009698

-5.13

0.001

Cell Cycle/growth control

   FGF receptor activating protein 1

U57715

-5.59

0.002

   BEST5 protein

Y07704

-2.37

0.003

   Peptide tyrosine-tyrosine (YY)

M17523

-3.91

0.002

   Glucagon gene

K02813

-6.58

0.002

   Epithelial membrane protein-1

Z54212

-3.47

0.017

   Neu oncogene

X03362

-1.58

0.05

Defense/immunity protein

   Beta defensin-1

AF068860

-42.16

0.001

AF093536

-10.2

0

Detoxification/antioxidation

   Glutathione S-transferase

J02810

-7.14

0

   Glutathione S-transferase Yb

X04229

-11.71

0.001

   Glutathione S-transferase, alpha 1

K01932

-4.18

0.004

   Glutathione S-transferase Yc1

S72505

-5.23

0.001

   Glutathione S-transferase Yc2

S72506

-5.27

0.012

S82820

-3.45

0.006

   Cytochrome P450 4F4 (CYP4F4)

U39206

-6.52

0.002

   Cytochrome P450CMF1b

J02869

-4.12

0.002

   Cytochrome P450 (CYP4F1)

M94548

-2.88

0.002

   1-Cys peroxiredoxin

Y17295

-2.55

0.002

   Metallothionein

M11794

-2.92

0.006

   D-amino-acid oxidase

AB003400

-5.42

0

   Peroxiredoxin 6

AF014009

-3.07

0.008

   Phenylalanine hydroxylase

M12337

-10.99

0.001

Metabolism

   Dipeptidase

L07315

-3.08

0.001

   Meprin beta-subunit

M88601

-3.27

0.001

   Disintegrin and metalloprotease domain 7

X66140

-14.03

0

Ligand binding/carrier

   Carnitine transporter

AB017260

-3.81

0.003

   Chloride channel (ClC-2)

AF005720

-3.26

0.001

   Putative potassium channel

AF022819

-2.69

0.001

   Mitochondrial dicarboxylate carrier

AJ223355

-2.54

0.01

   Aquaporin 3

D17695

-4.13

0

   Intestinal fatty acid binding protein

K01180

-4.43

0.005

   Na_H_Exchanger

L11236

-4.47

0.002

   H+, K+-ATPase

M90398

-2.52

0.001

   Carbonic anhydrase IV

S68245

-4.28

0.005

   Sodium transporter

X59677

-3.4

0

   Phosphatidylethanolamine binding protein

X75253

-2.69

0

Signal transduction

   B7 antigen

X76697

-170.95

0.002

   HCNP

E05646

-3.38

0

   Itmap1

AF022147

-7.97

0.005

   Guanylate cyclase activator 2A

M95493

-3.28

0.006

   Sgk

L01624

-2.76

0

Stress response/apoptosis

   Prostaglandin D synthetase

J04488

-45.8

0.01

Structure proteins

   Muc3

U76551

-3.56

0.01

   Intestinal mucin

M76740

-3.31

0.006

   Mucin-like protein

M81920

-3

0

   Plasmolipin

Z49858

-2.92

0.003

Transcription factor/regulator

   Testis specific X-linked gene

X99797

-6.91

0.003

Others

   Arginase II

U90887

-3.22

0

   3-phosphoglycerate dehydrogenase

X97772

-4.15

0.017

   Aldehyde dehydrogenase family 1

AF001898

-3.93

0.004