Table 2 Total number of cervical carcinoma cases screened for FGFR3 mutation, as of august 2004.
From: Clinical and biological characteristics of cervical neoplasias with FGFR3 mutation
Study | Method | Total number of cases | Mutated cases (percentage) |
|---|---|---|---|
Cappellen et al. [5] | SSCP (entire coding region) | 12 | 3 (25%) |
Yee et al. [9] | Direct sequencing (exon 7) | 104 | 0 |
Wu et al. [10] | Direct sequencing (exons 7, 10, 13, 15, and 19) | 51 | 1 (2%) |
Dai et al. [11] | Amplification created restriction site methodology for S249C mutation | 91 | 0 |
Sibley et al. [12] | Direct sequencing (exons 7, 10, and 15) | 28 | 1 (3.5%) |
Present study | SSCP (exons 7, 10, and 15) | 63 | 1 (1.5%) |
Total | 349 | 6 (1.7%) |