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Figure 3 | Molecular Cancer

Figure 3

From: A transcriptome map of cellular transformation by the fos oncogene

Figure 3

Expression of representative genes conditionally regulated in LacIv- fos cells and differentially expressed in both CMVc- fos cells and FBJ/R cells. Expression patterns of selected genes upregulated (A) or downregulated (B) specifically during conditional transformation, as well as in cells stably transformed by either c-Fos or v-Fos. Gene names are indicated above each pair of graphs. Line graphs indicate raw signal values obtained from the two independent LacIv-fos time course experiments. Time points at 24, 48 and 72 hours in the absence of IPTG (transforming) and at 24, 48 and 72 hours after the re-addition of IPTG (reverting) are indicated by arrows below each line graph. Bar graphs indicate raw signal values obtained in microarray analyses of the parental 208F fibroblast cell line (white), the stably transformed c-fos cell line (CMVc-fos; grey) and the stably transformed v-fos cell line (FBJ/R; black).

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