Table 2 Genes whose expression was downregulated (i.e., decreased by a factor ≥ 2) in FBJ/R cells (but not in CMVc-fos cells) and was conditionally regulated in LacIv-fos cells.
From: A transcriptome map of cellular transformation by the fos oncogene
Downregulated v-Fos-specific candidate genes | ||
|---|---|---|
GenBank Accession No. | Gene | Pattern |
M64780 | agrin | 5 |
M38135 | cathepsin H (RCHII) | 11 |
U52663 | peptidylglycine alpha-amidating monooxygenase (PAM) | 11 |
U75917 | clathrin-associated protein 17 (AP17) | 11 |
U75929 | SPARC (aka osteonectin)* | 11 |
X05341 | 3-oxoacyl-CoA thiolase | 11 |
D10026 | glutathione S-transferase Yrs-Yrs | 12 |
J02791 | acyl coenzyme A dehydrogenase medium chain | 12 |
J03752 | glutathione S-transferase | 12 |
M93257 | cathechol-O-methyltransferase | 12 |
X05472 | Rat 2.4 kb repeat DNA right terminal region | 12 |
X74593 | sorbitol dehydrogenase | 12 |
Y09333 | mitochondrial very-long-chain acyl-CoA thioesterase | 12 |
AF034218 | hyaluronidase (Hyal2) | 17 |
AF065387 | vitamin K-dependent gamma-glutamyl carboxylase | 17 |
J02810 | prostate glutathione S-transferase | 17 |
J05031 | isovaleryl-CoA dehydrogenase (IVD) | 17 |
L01702 | protein-tryosine-phosphatase (LRP) | 17 |
U10357 | pyruvate dehydrogenase kinase 2 subunit p45 (PDK2) | 17 |
U25651 | phosphofructokinase muscle isozyme | 17 |
U75928 | SPARC (aka osteonectin)* | 17 |
Y13714 | osteonectin (aka SPARC)* | 17 |
D00512 | mitochondrial acetoacetyl-CoA thiolase precursor | 18 |
D13921 | mitochondrial acetoacetyl-CoA thiolase | 18 |
D16309 | cyclin D3 | 18 |
M60921 | NGF-inducible anti-proliferative putative secreted protein (PC3) | 18 |
S7259 | tissue inhibitor of metalloproteinase type 2 | 18 |
X95986 | CBR gene | 18 |