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Table 1 Transcript abundance measurements for cultured normal BEC and BC cell lines

From: Variation in transcriptional regulation of cyclin dependent kinase inhibitor p21waf1/cip1 among human bronchogenic carcinomas

Sample Cell Type Medium Genetic Alterations Transcript Abundance
    p53 p16 p14 ARF Rb p73 c-myc E2F1 p73α p21
17378B N B        1,500 1 21,000
6F0333B N B        4,700 1 76,000
6F0395B N B        5,100 1 120,000
SW900 Sq R   I      7,300 100 12,000
Calu-1 Sq R I I      8,500 28 2,000
H460 LC R   I      9,000 14 18,000
H82 SC R I   I I   A 15,000 17 400
A549 A R   I I     16,000 1 6,200
A2126 A R I       17,000 30 6,100
N417 SC R I    I   A 19,000 5,200 34,000
H322 BA R I I      20,000 190 31,000
H446 SC R     I   A 67,000 710 120,000
H1155* LC R I    I I   50,000 250 470
H520 Sq R I I      56,000 120 2,300
H146 SC R     I    59,000 700 19,000
H661 LC R I I      76,000 210 58,000
A427** A R   I      180,000 220 100,000
  1. N, normal; Sq, squamous carcinoma; LC, large cell carcinoma; SC, small cell carcinoma; A, adenocarcinoma; BA, bronchoalveolar carcinoma; B, BEGM medium; R, RPMI with 10% FBS; I, inactivated; A, amplification. Non-detectable TA were entered as 1 to allow plotting on a logarithmic scale. Cell lines are grouped by increasing E2F1 TA. All values are in units of molecules/106 molecules β-actin and represent the mean from three independent measurements. *H1155 has a missense mutation in the transactivation domain of p73. **A427 has a deletion in the p73 coding sequence but the protein product still retains its transactivational function [35].