Figure 4
From: Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells
Tumor development in nu/nu mice on injection of HEK293 cells stably transfected with pcDNA3.1, pcDNA3.1PTTG or pcDNA3.1mPTTG1 cells. Each mouse was injected with 1 × 106 cells. After 6 weeks of injection, mice were photographed and sacrificed, tumors and other tissues were collected and tumor volume was measured a: Mouse injected with HEKpcDNA3.1 cells, b: mouse injected with HEKPTTG1-1 cells, c: mouse injected with HEKPTTG1-3 cells and d: mouse injected with HEKmPTTG1-2. Arrows indicate the tumors.