Figure 2From: hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancerImmunohistochemical detection of ZIP1 transporter protein in malignant and nonmalignant loci of a representative prostate cancer tissue section. (A) BPH, magnification is 1000Ă—, bar = 10 μm. (B) Normal, magnification is 400Ă—, bar = 25 μm. (C) PIN, magnification is 400Ă—, bars = 25 μm. (D) Adenocarcinoma, magnification 400Ă—, bar = 10 μm Note the immuno-positivity of the plasma membrane of BPH and normal glands. The malignant and PIN loci show no detectable ZIP1 so that the plasma membrane of these cells is not visible.Back to article page