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Table 1 ZIP1 immuno-positivity of glandular components in tissue sections of confirmed cases of prostate cancer.

From: hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer

Case no.

Grade

ZIP1 IHC scorea

  

Normal

PIN

BPH

Malignant

1

3

+++

 

+++

Negative

2

3

 

+

++

+

3

1

 

Negative

+

Negative

4

2

  

+

Negative

5

2

  

Negative

Negative

6

1

Negative

 

+++

Negative

7

2

++

 

+

+

8

1

  

+++

+

9

1

++

 

+++

Negative

10

2

  

+++

Negative

11

1

  

++

Negative

12

2

  

Negative

Negative

13

1

  

++

+

14

1

  

+

Negative

15

1

  

+

Negative

16

1

 

Negative

+

Negative

17

2

  

+++

+

18

1

 

+

++

+

19

1

  

+

Negative

20

1

  

+

Negative

21

2

 

+

+++

+

22

1

  

Negative

Negative

NEG ZIP1 IHC

  

3/22 (14%)

15/22 (68%)*

SCORES > +

3/4

0/6

11/22

0/22*

MEAN SCOREb

1.75

0.6

1.68(1.09)

0.32(0.48)*

  1. aScoring of immunoreactivity was done as follows: negative, no positive cells; score +, <10% positive cells; score ++, 10–50% positive cells; score +++, >50% positive cells
  2. bMEAN SCORE: MEAN(SD) for each group was obtained by the sum of the +'s/number of cases.
  3. * P < 0.01; BPH VS MALIGNANT GROUPS
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Molecular Cancer

ISSN: 1476-4598