Table 3 Translational opportunities from epigenetic alterations in cervical cancer
From: Epigenetics of cervical cancer. An overview and therapeutic perspectives
Early detection | Identification of a set of hypermethylated genes from cytological smears |
|---|---|
Prognostic/predictive | Determination of global methylation or histone modifications in tumor or peripheral blood cells Determination of hypermethylated gene promoters from serum/plasma DNA |
Therapy | DNA methylation inhibitors and/or HDACs inhibitors alone or as chemo- or radio-sensitizers |