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Figure 1 | Molecular Cancer

Figure 1

From: Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation

Figure 1

Schematic diagram of the MT3 promoter. The diagram was generated by downloading the MT3 CpG island genetic element with the addition of 200 bases upstream from http://genome.ucsc.edu/, using the Human July 2003 Freeze. The location of 5' UTR (â–¡), exon 1 and exon 2 (â– ) of MT3 (NM_005954) are shown. Each vertical line represents a CpG. The arrows represent the location of the 12 BstUI restriction enzyme sites analysed. The regions amplified for the 3 COBRA PCRs, R1, R2 and R3, are shown.

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