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Table 3 The incidence of MT3 methylation for the 64 patients with oesophageal SCC.

From: Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation

 

n

Unmethylated

Methylated

Male

45

22

23

Female

19

9

10

Age, median (range)

57 (42 – 76)

57 (46 – 76)

58 (42 – 70)

   Males

57 (42 – 70)

54 (46 – 68)

57 (42 – 70)

   Females

62 (49 – 76)

63 (49 – 76)

61 (50 – 68)

Tumour volume (cm3), median (range)

57 (4 – 300)

54 (4 – 300)

60 (4 – 225)

Histological differentiation

   

   Well/moderate

57

28

29

   Poor

4

2

2

   Not recorded

3

3

0

Tumour stage

   

   T1N0M0

3

1

2

   T2N0M0

9

5

4

   T2N1M0

3

2

1

   T2N2M0

1

1

0

   T3N0M0

29

13

16

   T3N1M0

9

6

3

   T3N2M0

1

0

1

   T3N2M1

1

0

1

   T4N0M0

2

2

0

   T4N0M1

1

0

1

   T4N1M0

2

1

1

   Not recorded

3

0

3