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Table 2 Genes in amplicons of chromosome 2, 8 and 20.

From: Identification of amplified and highly expressed genes in amplicons of the T-cell line huT78 detected by cDNA microarray CGH

Genes in amplicon of Chromosome 20

 

Unigene ID

Gene symbol

Position (Kb)*

Genomic values

Expression values

Genetic data**

Expression data**

20p13

Hs.356727

FKBP1A

-

1,918

4,022

0,940

2,008

 

Hs.155140

CSNK2A1

451

n.d.

1,678

n.d

0,747

 

Hs.156114

PTPNS1

1,505

1,635

0,868

0,709

-0,205

 

Hs.26045

PTPRA

2,832

1,279

0,251

0,355

-1,997

 

Hs.89648

AVP

3,051

n.d.

1,274

n.d

0,349

 

Hs.85004

CENPB

3,753

1,703

1,169

0,768

0,226

 

Hs.153752

CDC25B

3,765

2,122

1,761

1,079

0,811

 

Hs.80905

RASSF2

4,748

1,25

0,981

0,322

-0,028

 

Hs.78996

PCNA

5,083

1,694

8,187

0,760

3,033

 

Hs.2281

CHGB

5,880

n.d.

0,855

n.d

-0,226

 

Hs.73853

BMP2

6,737

2,694

n.d.

1,430

n.d

 

Hs.91143

JAG1

10,606

1,89

0,953

0,918

-0,069

 

Hs.44296

FLJ22324

13,761

1,543

2,292

0,626

1,197

 

Hs.82306

ADF

17,538

1,43

0,475

0,516

-1,075

 

Hs.268281

CRN

20,003

1,458

1,034

0,544

0,048

 

Hs.2030

THBD

23,016

1,655

0,572

0,727

-0,806

 

Hs.1872

PCK1

24,899

1,482

0,824

0,568

-0,279

 

Hs.274264

VSX1

25,044

1,67

1,682

0,740

0,750

 

Hs.75424

ID1

29,981

3,825

1,640

1,935

0,714

20q11

Hs.305890

BCL2L1

30,040

6,941

11,508

2,795

3,525

Genes in amplicon of chromosome 2

 

Unigene ID

Gene symbol

Position (Kb)*

Genomic values

Expression values

Genomic data**

Expression data**

2q34

Hs.54089

BARD1

218,722

0,734

1,646

-0,446

0,719

 

Hs.84981

XRCC5

220,094

1,823

2,815

0,856

1,341

 

Hs.162

IGFBP2

220,592

2,563

4,544

1,358

2,184

 

Hs.107169

IGFBP5

220,635

2,034

0,820

1,024

-0,285

 

Hs.38125

IFI75

224,000

1,342

1,664

0,413

0,647

 

Hs.309943

SP140

224,057

1,45

0,646

0,536

-0,631

 

Hs.83583

ARPC2

226,590

1,058

0,648

0,081

-0,626

 

Hs.166068

VIL1

226,796

1,025

1,463

0,036

0,549

 

Hs.82568

CYP27A1

227,154

1,676

0,764

0,745

-0,388

 

Hs.88049

PRKAG3

227,195

2,091

0,436

1,064

-1,196

 

Hs.153003

STK16

227,618

1,657

1,272

0,729

0,347

 

Hs.75318

TUBA1

227,622

1,631

5,622

0,706

2,491

 

Hs.77768

DNAJB2

227,652

1,82

0,841

0,864

-0,250

 

Hs.89655

PTPRN

227,662

1,659

1,447

0,730

0,533

 

Hs.48291

PDE6D

227,901

1,122

0,520

0,166

-0,943

 

Hs.1734

INHA

228,352

1,187

0,849

0,247

-0,237

 

Hs.198

PAX3

230,984

1,677

1,504

0,746

0,589

 

Hs.78946

CUL3

233,252

1,18

0,997

0,239

-0,004

 

Hs.75498

SCYA20

236,823

1,347

0,293

0,430

-1,769

 

Hs.91400

HDAC4

243,313

1,26

0,543

0,333

-0,881

 

Hs.36587

PPP1R7

244,757

0,907

1,859

-0,141

0,895

2q37

Hs.5345

RNPEPL1

245,348

1,488

0,949

0,573

-0,076

2q35

Hs.82793

PSMB3

-

1,794

3,874

0,843

1,954

Genes in amplicon of chromosome 8

 

Unigene ID

Gene symbol

Position (Kb)*

Genomic values

Expression values

Genomic data**

Expression data**

8q23

Hs.114218

FZD6

105,144

0,980

0,621

-0,030

-0,717

 

Hs.86905

ATP6C

105,407

1,067

0,918

0,094

-0,123

 

Hs.82173

TIEG

105,820

1,277

0,842

0,353

-0,248

 

Hs.94262

p53R2

106,237

1,324

0,564

0,369

-0,831

 

Hs.2463

ANGPT1

109,654

1,745

n.d

0,803

n.d.

 

Hs.106673

EIF3S6

111,104

1.170

0.402

0.227

-1.314

 

Hs.58189

EIF3S3

119,873

1,097

0,566

0,130

-0,885

 

Hs.184161

EXT1

121,031

1,260

3,592

0,333

1,845

 

Hs.174185

ENPP2

122,788

1,223

0,891

0,290

-0,167

 

Hs.12940

ZHX1

127,568

1,212

1,309

0,277

0,389

 

Hs.61661

-

127,822

1,101

1,318

0,139

0,399

 

Hs.181107

ANXA13

127,989

1,333

0,655

0,415

-0,611

 

Hs.344478

KIAA0196

129,211

1,302

n.d

0,381

n.d

 

Hs.79070

MYC

132,293

1,883

1,597

0,853

0,630

 

Hs.305916

TG

136,747

1,441

1,711

0,527

0,775

 

Hs.75789

NDRG1

137,117

1,617

1,140

0,693

0,190

 

Hs.157240

MGC4737

143,611

1,722

0,828

0,784

-0,273

 

Hs.740

PTK3

144,545

1,896

0,939

0,914

-0,487

 

Hs.77667

LY6E

146,427

1,595

2,410

0,674

1,269

 

Hs.301118

CYP11B1

146,498

1,619

1,227

0,695

0,295

 

Hs.348605

-

146,918

1,309

0,826

0,388

-0,276

 

Hs.264428

TSTA3

147,413

1,365

0,693

0,449

-0,530

 

Hs.223241

EEF1D

147,485

1,554

3,142

0,636

1,651

 

Hs.323834

NFKBIL2

147,600

1,375

4,436

0,459

2,149

 

Hs.339697

LOC51160

147,616

1,418

1,546

0,504

0,629

 

Hs.31442

RECQL4

147,653

1,458

3,419

0,544

1,774

 

Hs.12271

-

147,813

1,640

2,034

0,714

1,024

 

Hs.92679

-

147,876

1,178

1,510

0,236

0,595

8q24

Hs.331601

-

147,927

2,138

1,077

1,096

0,107

  1. Areas of genomic gain presenting the highest values are shown in bold. Note that in 20p amplicon, the entire region is gained, but only the highest values are indicated. Underlined are gained and overexpressed genes. * Map location according to the EnsMBL database (with exception of FKBP1A and PSMB3 genes that are FISH mapped); ** Log2 values; n.d. No data.