From: Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome
GeneBank Accession | Gene | Symbol | Normal Mean | Tumor Mean | Fold Change | P value |
---|---|---|---|---|---|---|
 | Cell Growth/Cycle |  |  |  |  |  |
X16323 | hepatocyte growth factor | HGF | 11 | 116 | 10.77 | 0.003305 |
AB017642 | oxidative-stress responsive 1 | OSR1 | 58 | 428 | 7.41 | 0.000819 |
AL078641 | phorbolin-like protein | APOBEC3G | 15 | 92 | 6.21 | 0.000158 |
L17128 | gamma-glutamyl carboxylase | GGCX | 64 | 346 | 5.37 | 0.000018 |
D21089 | xeroderma pigmentosum, complementation group C | XPC | 292 | 1278 | 4.38 | 0.000284 |
AL050223 | vesicle-associated membrane protein 2 | VAMP2 | 360 | 1533 | 4.26 | 0.002196 |
D38145 | prostaglandin I2 synthase | PTGIS | 29 | 121 | 4.09 | 0.000448 |
AF092563 | structural maintenance of chromosomes 2-like 1 | SMC2L1 | 58 | 185 | 3.21 | 0.002352 |
AF006087 | actin related protein 2/3 complex, subunit 4 | ARPC4 | 292 | 865 | 2.96 | 0.000565 |
AC004537 | inhibitor of growth family, member 3 | ING3 | 46 | 114 | 2.47 | 0.003976 |
AF013168 | tuberous sclerosis 1 | TSC1 | 35 | 86 | 2.45 | 0.001232 |
AJ236876 | ADP-ribosyltransferase polymerase)-like 2 | ADPRTL2 | 32 | 76 | 2.34 | 0.003874 |
 | Cell Death/Apoptosis |  |  |  |  |  |
D38435 | postmeiotic segregation increased 2-like | PMS2L1 | 74 | 193 | 2.6 | 0.002976 |
M61906 | phosphoinositide-3-kinase, regulatory subunit | PIK3R1 | 43 | 104 | 2.4 | 0.004387 |
 | Signal Transduction |  |  |  |  |  |
U26710 | Cas-Br-M ectropic retroviral transforming sequence b | CBLB | 21 | 177 | 8.4 | 0.000082 |
AB010414 | guanine nucleotide binding protein, gamma 7 | GNG7 | 59 | 334 | 5.68 | 0.003835 |
U59913 | mothers against decapentaplegic homolog 5 | MADH5 | 14 | 73 | 5.22 | 0.004731 |
AB004922 | Homo sapiens gene for Smad 3 | MADH3 | 93 | 443 | 4.76 | 0.001024 |
L11672 | zinc finger protein 91 | ZNF91 | 428 | 2007 | 4.69 | 0.000376 |
D14838 | fibroblast growth factor 9 | FGF9 | 27 | 108 | 3.97 | 0.000752 |
W27899 | member RAS oncogene family | RAB6B | 68 | 232 | 3.43 | 0.00501 |
U48251 | protein kinase C binding protein 1 | PRKCBP1 | 40 | 127 | 3.18 | 0.001999 |
U90268 | cerebral cavernous malformations 1 | CCM1 | 53 | 151 | 2.87 | 0.004392 |
AL050275 | cysteine rich with EGF-like domains | CRELD1 | 195 | 543 | 2.79 | 0.000828 |
AB014600 | SIN3 homolog B, transcriptional regulator | SIN3B | 177 | 425 | 2.39 | 0.001924 |
M27691 | cAMP responsive element binding protein 1 | CREB1 | 107 | 229 | 2.15 | 0.003559 |
U85245 | phosphatidylinositol-4-phosphate 5-kinase, type II, beta | PIP5K2B | 244 | 518 | 2.12 | 0.000441 |
W25793 | ring finger protein 3 | RNF3 | 163 | 326 | 2 | 0.004947 |
 | Nucleic Acid Binding |  |  |  |  |  |
D50912 | RNA binding motif protein 10 | RBM10 | 96 | 443 | 4.6 | 0.001925 |
U41315 | makorin, ring finger protein, 4 | MKRN4 | 404 | 808 | 2 | 0.000262 |
 | Ligand Binding |  |  |  |  |  |
X67155 | kinesin-like 5 | KIF23 | 64 | 368 | 5.76 | 0.001584 |
AB028985 | ATP-binding cassette, sub-family A, member 2 | ABC1 | 65 | 262 | 4.04 | 0.001234 |
Z48482 | matrix metalloproteinase 15 | MMP15 | 139 | 495 | 3.56 | 0.003946 |
 | Enzyme |  |  |  |  |  |
X13794 | lactate dehydrogenase B | LDHB | 396 | 1606 | 4.05 | 0.000845 |
X15334 | creatine kinase, brain | CKB | 939 | 2083 | 2.22 | 0.002008 |
X60708 | dipeptidylpeptidase IV | DPP4 | 133 | 291 | 2.19 | 0.000697 |
AC004381 | SA homolog | SAH | 283 | 599 | 2.11 | 0.000168 |
AF000416 | exostoses-like 2 | EXTL2 | 134 | 271 | 2.02 | 0.001314 |
 | Embryogenesis |  |  |  |  |  |
U48437 | amyloid beta precursor-like protein 1 | APLP1 | 851 | 2433 | 2.86 | 0.001043 |
U66406 | ephrin-B3 | EFNB3 | 168 | 438 | 2.6 | 0.00309 |
D50840 | UDP-glucose ceramide glucosyltransferase | UGCG | 85 | 211 | 2.5 | 0.002554 |
 | Other/Unknown |  |  |  |  |  |
L48215 | hemoglobin, beta | HBB | 12 | 2099 | 178.78 | 0.001299 |
J00153 | hemoglobin, alpha 1 | HBA1 | 15 | 1249 | 82.25 | 0.001889 |
U30521 | P311 protein | C5orf13 | 157 | 453 | 2.88 | 0.001431 |
AB011169 | similar to S. cerevisiae SSM4 | TEB4 | 140 | 300 | 2.15 | 0.00154 |
AL031432 | GCIP-interacting protein | P29 | 99 | 198 | 2 | 0.002036 |