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Table 7 Genes significantly decreased in tumors (continued).

From: Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome

GeneChip Accession Gene Description Symbol Normal Mean Tumor Mean Fold Change P value
  Enzyme      
M81057 carboxypeptidase B1 CPB1 4534 79 -57.09 0.001106
X71345 protease, serine, 4 PRSS3 3859 76 -51.11 0.004102
X01683 serine (or cysteine) proteinase inhibitor, clade A SERPINA1 2550 74 -34.64 0.004833
M24400 chymotrypsinogen B1 CTRB1 5158 207 -24.95 0.001744
M18700 elastase 3A, pancreatic ELA3A 7058 384 -18.37 0.000009
U66061 protease, serine, 1 PRSS1 7291 645 -11.31 0.000047
L22524 matrix metalloproteinase 7 MMP7 595 54 -11.03 0.002591
AI655458 5-oxoprolinase (ATP-hydrolysing) OPLAH 446 99 -4.52 0.004072
H94881 FXYD domain-containing ion transport regulator 2 FXYD2 3116 708 -4.40 0.000539
AL021026 flavin containing monooxygenase 2 FMO2 905 215 -4.21 0.000804
AC005525 plasminogen activator, urokinase receptor PLAUR 1779 566 -3.14 0.000031
U40370 phosphodiesterase 1A, calmodulin-dependent PDE1A 268 89 -3.03 0.004023
R90942 sialyltransferase 7D SIAT7D 3148 1052 -2.99 0.002319
M84472 hydroxysteroid (17-beta) dehydrogenase 1 HSD17B1 1196 440 -2.72 0.000991
X55988 ribonuclease, RNase A family, 2 RNASE2 480 203 -2.36 0.001314
AB003151 carbonyl reductase 1 CBR1 4538 1945 -2.33 0.000511
X08020 glutathione S-transferase M1 GSTM1 2766 1376 -2.01 0.000519
  Embryogenesis      
U15979 delta-like homolog SIGLEC5 3384 402 -8.41 0.002927
M60094 H1 histone family, member T HIST1H1T 976 230 -4.23 0.001639
U50330 bone morphogenetic protein 1 BMP1 3298 973 -3.39 0.001637
M74297 homeo box A4 HOXA4 501 176 -2.85 0.000477
AJ011785 sine oculis homeobox homolog 6 SIX6 530 190 -2.79 0.000286
U66198 fibroblast growth factor 13 FGF13 191 73 -2.61 0.001068
D31897 double C2-like domains, alpha DOC2A 1151 451 -2.55 0.000068
U12472 glutathione S-transferase pi GSTP1 3122 1524 -2.05 0.000237
  Transcription      
AL049228 pleckstrin homology domain interacting protein PHIP 257 33 -7.69 0.000782
M27878 zinc finger protein 84 ZNF84 54 15 -3.64 0.001108
U77629 achaete-scute complex-like 2 ASCL2 438 184 -2.38 0.000058
D50495 transcription elongation factor A, 2 TCEA2 1330 595 -2.23 0.000019
U49857 transcriptional activator of the c-fos promoter CROC4 542 259 -2.09 0.003894