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Figure 6 | Molecular Cancer

Figure 6

From: Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo

Figure 6

Combination drug effects of DMC with CPT-11 or temozolomide. U251 and LN229 glioblastoma cells were treated with DMC, CPT-11, and temozolomide (TMZ) either alone or in combination as indicated for 48 hours. The percentage of surviving cells was established by the conventional colony forming assay, where the number of surviving cells able to spawn a colony of newly grown cells was determined two weeks after drug treatment. Shown are the results from one experiment performed in triplicate, which was repeated several times with very similar results.

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Molecular Cancer

ISSN: 1476-4598