Table 1 Associations between BRAF mutation and clinicopathological features of colorectal cancer.
Feature (n) a | BRAF wild-type (%) | BRAF mutation (%) | P |
|---|---|---|---|
Total (275) | 252 (92) | 23 (8) | |
Age (yrs) | 68.4 ± 13.0 | 68.4 ± 20.7 | NS |
Gender | |||
Men (132) | 124 (94) | 8 (6) | |
Women (100) | 87 (87) | 13 (13) | 0.068 |
Infiltrating lymphocytes | |||
Negative (199) | 190 (95) | 9 (5) | |
Positive (21) | 11 (52) | 10 (48) | <0.0001 |
Nodal involvement | |||
Negative (128) | 115 (90) | 13 (10) | |
Positive (70) | 66 (94) | 4 (6) | NS |
Tumor site | |||
Proximal (93) | 79 (85) | 14 (15) | |
Distal (126) | 122 (97) | 4 (3) | 0.0015 |
Histological grade | |||
Well/moderate (140) | 133 (95) | 7 (5) | |
Poor (29) | 22 (76) | 7 (24) | 0.0006 |
Mucinous | |||
Negative (159) | 150 (94) | 9 (6) | |
Positive (27) | 20 (74) | 7 (26) | 0.0005 |