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Table 1 Associations between BRAF mutation and clinicopathological features of colorectal cancer.

From: BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status

Feature (n) a BRAF wild-type (%) BRAF mutation (%) P
Total (275) 252 (92) 23 (8)  
Age (yrs) 68.4 ± 13.0 68.4 ± 20.7 NS
Gender    
   Men (132) 124 (94) 8 (6)  
   Women (100) 87 (87) 13 (13) 0.068
Infiltrating lymphocytes    
   Negative (199) 190 (95) 9 (5)  
   Positive (21) 11 (52) 10 (48) <0.0001
Nodal involvement    
   Negative (128) 115 (90) 13 (10)  
   Positive (70) 66 (94) 4 (6) NS
Tumor site    
   Proximal (93) 79 (85) 14 (15)  
   Distal (126) 122 (97) 4 (3) 0.0015
Histological grade    
   Well/moderate (140) 133 (95) 7 (5)  
   Poor (29) 22 (76) 7 (24) 0.0006
Mucinous    
   Negative (159) 150 (94) 9 (6)  
   Positive (27) 20 (74) 7 (26) 0.0005
  1. a Data was unavailable for gender in 43 cases, infiltrating lymphocytes in 55 cases, nodal involvement in 77 cases, tumor site in 56 cases, grade in 106 cases and mucinous appearance in 89 cases.