Table I Expression of Cdc14A protein in human cancer cell lines as determined by Western blot using anti-hCdc14A antibodies (Ab-2).
Cell lines | Tumor type | Cdc14A expression | P53 status |
|---|---|---|---|
MCF-7 | breast | high | wt |
MCF7/ADR-RES | Â | very high | mt |
MDA-MB-231 | Â | high | mt |
MDA-MB-435 | Â | not detected | mt |
HS 578T | Â | not detected | mt |
T-47D | Â | low | mt |
BT-549 | Â | high | ? |
MCF-7* | Â | high | wt |
MCF-10* | Â | not detected | wt |
SUM-44* | Â | low | ? |
SUM-468* | Â | high | mt |
MDA-MB-436* | Â | low | mt |
A549/ATCC | lung | low | wt |
NCI-H460 | Â | not detected | wt |
NCI-H23 | Â | not detected | mt |
NCI-H322M | Â | not detected | mt |
EKVX | Â | not detected | mt |
NCI-H226 | Â | high | mt |
HCI-H522 | Â | not detected | mt |
HOP-62 | Â | high | mt |
HOP-92 | Â | high | mt |
HCT-116 | colon | low | wt |
HCT-15 | Â | low | wt/mt |
HT29 | Â | high | mt |
HCC2998 | Â | high | mt |
SW-620 | Â | not detected | mt |
COLO 205 | Â | low | mt |
KM12 | Â | low | mt |
HCT-116* | Â | high | wt |
HCT-116 p53-/-* | Â | high | null |
RKO* | Â | low | wt |
HT29* | Â | high | mt |
ACHN | kidney | not detected | wt |
UO-31 | Â | low | wt |
RXF-393 | Â | low | mt |
CAKI-1 | Â | high | wt |
SN12C | Â | high | mt |
786-0 | Â | high | mt |
TK-10 | Â | high | mt |
A498 | Â | low | wt |
OVCAR-4 | ovary | not detected | wt |
IGROV1 | Â | low | wt |
OVCAR-3 | Â | high | mt |
OVCAR-8 | Â | very high | mt |
OVCAR-5 | Â | high | mt |
SK-OV-3 | Â | low | mt |
SF-539 | CNS | high | wt |
SF-295 | Â | high | mt |
SF-268 | Â | low | mt |
SNB-75 | Â | high | mt |
SNB-19 | Â | not detected | mt |
U251 | Â | high | mt |
MOLT-4 | leukemia | not detected | wt |
SR | Â | high | wt |
RPMI-8226 | Â | high | mt |
HL-60(TB) | Â | not detected | mt |
K-562 | Â | low | mt |
CCRF – CEM |  | not detected | mt |
MALME-3M | melanoma | low | wt |
SK-MEL-5 | Â | not detected | wt |
UACC-62 | Â | not detected | wt |
LOX IMVI | Â | low | wt |
SK-MEL-28 | Â | not detected | mt |
M14 | Â | not detected | mt |
UACC-257 | Â | not detected | wt |
SK-MEL-2 | Â | not detected | wt |
DU-145 | prostate | high | mt |
PC-3 | Â | high | mt |
PC-3* | Â | low | mt |
LNCaP* | Â | low | wt |
J82* | bladder | very high | mt |
SK-N-SH* | neroblastoma | low | wt |
Sk-N-MC* | Â | low | wt |
IMR32* | Â | not detected | wt |
SHSY-SY* | Â | low | wt |
Normal fibroblasts (NF)* | others | low | wt |
COS* | Â | not detected | wt |