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Figure 3 | Molecular Cancer

Figure 3

From: Hypoxia-inducible factor-1α polymorphisms and TSC1/2 mutations are complementary in head and neck cancers

Figure 3

Immmunohistochemical staining of SCC tumors. Immunostaining for HIF-1α (SC10790), (Santa Cruz Biotech., Inc. Santa Cruz, CA, USA) was performed on 5 μM sections. Staining was analyzed with horseradish peroxidase-linked goat antimouse (Santa Cruz Biotechnology, Santa Cruz, CA) Tumors lacking HIF-1α (top panel) and tumors that manifest an exon 12 HIF-1α polymorphism and TSC deletions in exon 36 and 40 (bottom panel).

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