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Table 2 Summary of SCC cell lines

From: Hypoxia-inducible factor-1α polymorphisms and TSC1/2 mutations are complementary in head and neck cancers

Cell Lines

TSC1/TSC2

Nucleotide Change

Type of Mutation

HIF-1α Nucleotide Change

Type of Mutation

SSC4a

Exon

17(TSC1)

40 (TSC2)

41 (TSC2)

2111_2112delAT (TSC1);

5238_5255del

G5346C

Frameshift in-frame deletion

Polymorphism

NC

NC

SSC9

NC

NA

NA

NC

NC

SSC15

NC

NA

NA

NC

NC

SCC25b

Exon

40(TSC2)

5238_5255del

in-frame deletion

NC

NC

UMBSSC11

NC

NA

NA

NC

NC

  1. WD-Well differentiated;MD-Moderately Well-differentiated; UD-Undifferentiated;NC-No change wild-type; P-polymorphism; M-Mutation; del-deletion