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Figure 10 | Molecular Cancer

Figure 10

From: Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors

Figure 10

Down-regulation of c-Myc by U0126 in non-muscle tumor cell lines. A. Total lysates from the indicated non-muscle tumor cell lines untreated (-) or treated (+) with 10 μM U0126 for indicated times were analysed by immunoblotting with anti-c-Myc, anti-pospho-c-Myc, anti-ERKs and anti pospho-ERKs. B. Total lysates from untransformed C2C12 and NIH3T3 were analysed by immunoblotting with anti-c-Myc, anti-ERKs and anti pospho-ERKs. α-tubulin expression shows the loading of samples. Similar results were obtained in two experiments.

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Molecular Cancer

ISSN: 1476-4598