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Table 4 Expression in Islands frequently deleted in CRC.

From: A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer

chromosomal region fraction of patients with deletions congruent with our expression data CGH study
1p   yes [17]
1p36.2-1p36.1 21% yes [22]
1p21-1p22 72% no [21, 24]
3p12 66% no [21, 24]
4 yes [15, 17, 18]
4p 42% yes [19]
4p14 87% yes [21, 24]
4q 58% yes [19]
4q27-4q28 96% no [21, 24]
4q31.3 39% no [22]
4q34.3 38% yes [25]
4q35 34% yes [22]
5q > 35% yes [17, 23]
5q21 81% yes [21, 24]
6q16-6q21 72% no [21, 24]
8p 37% no [17, 18, 23, 25]
8p24-8p21 66% no [21, 24]
9p21 64% yes [21, 24]
9p22 25% no [22]
10q26.2 22% no [25]
11q13.1 30% no [25]
14q   yes [17]
14q13-14q21 64% yes [21, 24]
15q   yes [17]
17p 46% yes [23]
17p13.2 51% yes [25]
17p12 32% yes [25]
18   yes [17]
18p 49% yes [23]
18q 60% yes [23]
18q 32% yes [18, 25]
18q 92% yes [19]
18q11.2 72% no [22]
18q12.2 59% no [25]
18q21-18q23 96% yes [21]
18q21.1 60% yes [25]
21q > 35% yes [23]
21q21 74% no [21, 24]
  1. Literature survey of chromosomal regions with evidence for deletions in colorectal cancers. We checked all regions of frequent chromosomal deletions for congruence with expression patterns. Congruence between literature CGH data and our expression data was declared on the presumption that allelic loss causes mRNA down-regulation.