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Table 3 Frequent copy number and expression altered genes1.

From: Identification of novel candidate target genes in amplicons of Glioblastoma multiforme tumors detected by expression and CGH microarray profiling

GAINED AND OVEREXPRESSED GENES
SYMBOL GENE DESCRIPTION % MEDIAN LOCATION
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 20.00 1.17 1q25-q32
LOC153222 Adult retina protein 25.00 1.32 5
GBAS Glioblastoma amplified sequence 20.00 1.61 7p12
GUSB Glucuronidase, beta 20.00 1.42 7q21.11
RFC2 Replication factor C (activator 1) 2, 40kDa 26.32 1.06 7q11.23
MCM7 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) 35.29 1.02 7q21.3-q22.1
GIMAP6 GTPase, IMAP family member 6 20.00 1.29  
LR8 LR8 protein 21.05 2.34 7q36.1
APOE Apolipoprotein E 22.22 1.48 19q13.2
EMP3 Epithelial membrane protein 3 33.33 1.36 19q13.3
FPR1 Formyl peptide receptor 1 25.00 1.94 19q13.4
LOST AND UNDEREXPRESSED GENES
SYMBOL GENE DESCRIPTION % MEDIAN LOCATION
CYP1B1 Cytochrome P450, family 1, subfamily B, polypeptide 1 21.05 -2.87 2p21
TDE2 Tumor differentially expressed 2 23.53 -1.86 6q22.32
OPTN Optineurin 41.18 -1.86 10p14
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 25.00 -1.16 10
SIRT1 Sirtuin (silent mating type information regulation 2 homolog) 1 27.27 -1.27 10q22.1
PPP3CB Protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform 35.00 -2.08 10q21-q22
GHITM Growth hormone inducible transmembrane protein 37.50 -1.55 10q23.2
CYP26A1 Cytochrome P450, family 26, subfamily A, polypeptide 1 21.05 -1.08 10q23-q24
LGI1 Leucine-rich, glioma inactivated 1 45.00 -1.32 10q24
SLK STE20-like kinase (yeast) 26.32 -1.11 10q25.1
ADD3 Adducin 3 (gamma) 68.42 -1.04 10q24.2-q24.3
MXI1 MAX interactor 1 40.00 -1.11 10q24-q25
ATRNL1 Attractin-like 1 30.77 -1.65 10
KIAA1598 KIAA1598 21.05 -1.83 10q26.12
NDFIP2 Nedd4 family interacting protein 2 33.33 -1.22 13q22.2
MAP2K4 Mitogen-activated protein kinase kinase 4 23.53 -1.30 17p11.2
DSG2 Desmoglein 2 31.25 -1.94 18q12.1
TPTE Transmembrane phosphatase with tensin homology 22.22 -1.67 21p11
  1. 1Percentage of tumors showing copy number and expression alterations (%). Median of expression log2 ratios of copy number altered genes (median).