Table 4 Enriched processes and pathways identified with the Jubilant PathArt database using proteins which were significantly altered in ccRCC as compared to normal tissue, with p< 0.05.
From: Pathway analysis of kidney cancer using proteomics and metabolic profiling
| Process or Pathway (Jubilant PathArt) | RCC Proteins | H. sapiens Ref. | pValue |
|---|---|---|---|
| Glycolysis/Gluconeogenesis | 7 | 34 | < 1.00E-05 |
| Propanoate Metabolism | 5 | 33 | 1.00E-05 |
| Pyruvate Metabolism | 5 | 37 | 1.00E-05 |
| Arginine And Proline Metabolism | 4 | 62 | 2.00E-05 |
| Urea Cycle | 4 | 38 | 2.00E-05 |
| p53 Mediated Pathway | 6 | 154 | 3.20E-04 |
| Butanoate Metabolism | 3 | 41 | 0.00196 |
| Citrate Cycle | 3 | 43 | 0.00224 |
| Sterol, Vitamin K, Vitamin E, Carotenoids Biosynthesis | 3 | 46 | 0.00271 |
| Lysine Degradation | 3 | 54 | 0.00422 |
| Valine, Leucine And Isoleucine Degradation | 3 | 56 | 0.00466 |
| Purine Metabolism | 4 | 121 | 0.00582 |
| FAS Signaling Pathway | 3 | 136 | 0.04344 |