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Table 4 Enriched processes and pathways identified with the Jubilant PathArt database using proteins which were significantly altered in ccRCC as compared to normal tissue, with p< 0.05.

From: Pathway analysis of kidney cancer using proteomics and metabolic profiling

Process or Pathway (Jubilant PathArt) RCC Proteins H. sapiens Ref. pValue
Glycolysis/Gluconeogenesis 7 34 < 1.00E-05
Propanoate Metabolism 5 33 1.00E-05
Pyruvate Metabolism 5 37 1.00E-05
Arginine And Proline Metabolism 4 62 2.00E-05
Urea Cycle 4 38 2.00E-05
p53 Mediated Pathway 6 154 3.20E-04
Butanoate Metabolism 3 41 0.00196
Citrate Cycle 3 43 0.00224
Sterol, Vitamin K, Vitamin E, Carotenoids Biosynthesis 3 46 0.00271
Lysine Degradation 3 54 0.00422
Valine, Leucine And Isoleucine Degradation 3 56 0.00466
Purine Metabolism 4 121 0.00582
FAS Signaling Pathway 3 136 0.04344