Figure 6From: Altered Ca2+ homeostasis in polymorphonuclear leukocytes from chronic myeloid leukaemia patientsCartoon depicting Intracellular Ca2+ signalling network. Binding of ligand to the seven transmembrane domain receptors activates release of calcium from intracellular stores through IP3 signalling pathway or ryanodine receptors and also initiates influx of calcium through various channels. Increase in Ca2+ results in various cellular responses.Back to article page