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Table 1 Different gene mRNA expression on CD133+ cells compared to those on autologous CD133- cells *

From: Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

   No. 66 No. 377 No. 1049
Section Gene name CD133- CD133+ CD133- CD133+ CD133- CD133+
A CD90 1 15.6 ± 0.66 1 12.8 ± 0.94 1 13.5 ± 0.75
  CD44 1 5.7 ± 0.48 1 2.5 ± 0.22 1 2.8 ± 0.19
  CXCR4 1 337.8 ± 29.2 1 251.5 ± 22.1 1 264.9 ± 22.9
  Nestin 1 21.4 ± 1.25 1 23.2 ± 1.65 1 22.1 ± 1.54
  MSI 1 84 ± 7.6 1 75.4 ± 7.03 1 53.5 ± 6.2
  MELK 1 1351 ± 95.8 1 467.7 ± 40.5 1 514.6 ± 45.6
  GLI-1 1 46 ± 3.8 1 43 ± 4.5 1 49 ± 5.9
  PTCH 1 16 ± 1.48 1 13.5 ± 0.85 1 14.3 ± 1.24
B MGMT 1 32.4 ± 2.5 1 34.7 ± 2.9 1 56.3 ± 4.2
  BCRP1 1 6.5 ± 0.43 1 4.3 ± 0.25 1 4.8 ± 0.24
  SIRT1 1 4.9 ± 0.34 1 4.2 ± 0.26 1 5.4 ± 0.29
  FLIP 1 294 ± 25.5 1 157.6 ± 14.2 1 145.6 ± 13.7
  BCL-2 1 13.9 ± 0.95 1 4.9 ± 0.54 1 3.8 ± 0.54
  BCL-XL 1 5.6 ± 0.39 1 3.2 ± 0.16 1 2.5 ± 0.14
  cIAP1 1 39.0 ± 3.5 1 4.3 ± 0.53 1 5.6 ± 0.65
  cIAP2 1 3 ± 0.25 1 1.9 ± 0.12 1 1.7 ± 0.14
  XIAP 1 21.9 ± 2.2 1 9.7 ± 0.68 1 10.3 ± 0.91
  NAIP 1 12.1 ± 0.75 1 6.4 ± 0.43 1 4.5 ± 0.62
  Survivin 1 1.6 ± 0.08 1 2.3 ± 0.18 1 2.4 ± 0.18
  BAX 1 0.33 ± 0.03 1 0.49 ± 0.06 1 0.21 ± 0.05
  1. * Total RNA was extracted from both CD133+ and CD133- fraction after FACS sorting from three primary cultured cells (No. 66, 377 and 1049). Different gene mRNA expression was measured by real-time qPCR. The relative mRNA expression of different gene in CD133+ cells was presented as the fold increase compared to that of autologous CD133- cells (see Methods). Data was presented as Mean ± SD of three independent experiments.