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Figure 14 | Molecular Cancer

Figure 14

From: Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling

Figure 14

MT1-MMP is required for tumor cell movement when cells are embedded within 3D collagen matrices. Representative individual 24 hour tracings (illustrated in Fig. 7) of Luciferase or custom MT1-MMP siRNA transfected Nuc-GFP HT1080 cells embedded in 3D collagen matrices are presented (grayscale). Images were acquired every 10 minutes. Magnification = 20×. Scale bars = 100 μm.

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Molecular Cancer

ISSN: 1476-4598