Table 2 Gene Transcripts significantly up-regulated in BCC compared to normal skin specimens (≥1.2 fold; ≥100; p < 0.05).
From: Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays
probe set | gene | Accession | fold change | Difference | P value |
|---|---|---|---|---|---|
204697_s_at | chromogranin A (parathyroid secretory protein 1) | NM_001275 | 130.34 | 2497.11 | 0.000001 |
224590_at | X (inactive)-specific transcript | BE644917 | 69.08 | 427.18 | 0.001884 |
214218_s_at | X (inactive)-specific transcript | AV699347 | 62.79 | 621.31 | 0.00072 |
242964_at | gb:AI421677/DB_XREF=gi:4267608/DB_XREF=tf54a03.x1/CLONE | AI421677 | 55.54 | 730.97 | 0.000005 |
224588_at | X (inactive)-specific transcript | AA167449 | 49.82 | 2086.08 | 0.000552 |
204913_s_at | SRY (sex determining region Y)-box 11 | AI360875 | 27.92 | 228.19 | 0.000224 |
1560652_at | gb:AL832136.1/DB_XREF=gi:21732679/TID=Hs2.407141.1/CNT=4 | AL832136 | 26.21 | 638.38 | 0.000015 |
236029_at | FAT tumor suppressor homolog 3 (Drosophila) | AI283093 | 24.03 | 916.82 | 0.000015 |
214913_at | a disintegrin-like and metalloprotease (reprolysin type) | AB002364 | 23.97 | 605.9 | 0.000002 |
220345_at | leucine rich repeat transmembrane neuronal 4 | NM_024993 | 22.24 | 270.15 | 0.0061 |
233622_x_at | Transcribed locus, weakly similar to XP_375099.1 hypothetical protein | AL162077 | 21.31 | 105.45 | 0.005425 |
230863_at | gb:R73030/DB_XREF=gi:847062/DB_XREF=yj94c11.s1/CLONE= | R73030 | 20.05 | 292.94 | 0.029359 |
204915_s_at | SRY (sex determining region Y)-box 11 | AB028641 | 19.64 | 524.92 | 0.000059 |
204424_s_at | LIM domain only 3 (rhombotin-like 2) | AL050152 | 19.19 | 1287.59 | 0.003562 |
236407_at | gb:R73518/DB_XREF=gi:847550/DB_XREF=yj93h12.s1/CLONE= | R73518 | 18.1 | 355.25 | 0.000003 |
208025_s_at | high mobility group AT-hook 2///high mobility group AT-hook 2 | NM_003483 | 17.76 | 506.18 | 0.000173 |
215311_at | MRNA full length insert cDNA clone EUROIMAGE 21920 | AL109696 | 17.1 | 448.46 | 0.000013 |
227671_at | X (inactive)-specific transcript | AV646597 | 16.98 | 383.7 | 0.003059 |
218638_s_at | spondin 2, extracellular matrix protein | NM_012445 | 16.91 | 2992.93 | 0 |
208212_s_at | anaplastic lymphoma kinase (Ki-1) | NM_004304 | 16.76 | 835.41 | 0.000003 |
226346_at | gb:AA527151/DB_XREF=gi:2269220/DB_XREF=ni07b08.s1/CLONE | AA527151 | 15.34 | 534.55 | 0 |
204914_s_at | SRY (sex determining region Y)-box 11 | AW157202 | 15.1 | 310.64 | 0.000124 |
215443_at | thyroid stimulating hormone receptor | BE740743 | 14.95 | 239.99 | 0.00019 |
240460_at | gb:AI190616/DB_XREF=gi:3741825/DB_XREF=qd38e02.x1/CLONE | AI190616 | 14.91 | 168.09 | 0.000564 |
1562107_at | hypothetical protein MGC14738 | BC007100 | 14.73 | 284.47 | 0.000263 |
213960_at | CDNA FLJ37610 fis, clone BRCOC2011398 | T87225 | 14.18 | 534.88 | 0.000001 |
1565936_a_at | LIM domain only 3 (rhombotin-like 2) | T24091 | 13.94 | 162.48 | 0.001811 |
229523_at | gb:N66694/DB_XREF=gi:1218819/DB_XREF=yy71g08.s1/CLONE= | N66694 | 13.82 | 614.51 | 0.000001 |
210055_at | thyroid stimulating hormone receptor | BE045816 | 13.81 | 181.7 | 0.000595 |
224646_x_at | gb:BF569051/DB_XREF=gi:11642431/DB_XREF=602184410T1/ | BF569051 | 13.81 | 1024.01 | 0.000261 |
207468_s_at | secreted frizzled-related protein 5 | NM_003015 | 13.54 | 437.41 | 0.001339 |
220518_at | target of Nesh-SH3 | NM_024801 | 13.44 | 448.75 | 0.001398 |
224997_x_at | H19, imprinted maternally expressed untranslated mRNA | AL575306 | 13.39 | 1131.86 | 0.000494 |
222940_at | sulfotransferase family 1E, estrogen-preferring, member 1 | U55764 | 13.29 | 560.15 | 0.000001 |
235795_at | gb:AW088232/DB_XREF=gi:6044037/DB_XREF=xc99c09.x1 | AW088232 | 13.26 | 199.49 | 0.000451 |
220090_at | chromosome 1 open reading frame 10 | NM_016190 | 12.79 | 736.69 | 0.00414 |
238584_at | IQ motif containing with AAA domain | W52934 | 12.68 | 222.06 | 0.001169 |
203878_s_at | matrix metalloproteinase 11 (stromelysin 3) | NM_005940 | 12.23 | 685.83 | 0.000417 |
1557215_at | Transcribed locus, weakly similar to XP_375935.1 hypothetical protein | AK056212 | 11.92 | 262.54 | 0.003503 |
210292_s_at | protocadherin 11 Y-linked///protocadherin 11 X-linked | AF332218 | 11.83 | 211.94 | 0.000324 |
1558964_at | FAT tumor suppressor homolog 3 (Drosophila) | AA334950 | 11.22 | 280.34 | 0.000123 |
214451_at | transcription factor AP-2 beta (activating enhancer binding protein 2 | NM_003221 | 10.67 | 2196.21 | 0 |
209816_at | patched homolog (Drosophila) | AL044175 | 10.59 | 245.97 | 0.001175 |
241617_x_at | gb:BE961949/DB_XREF=gi:11764352/DB_XREF=601655369R1 | BE961949 | 10.43 | 1011 | 0.000972 |
209815_at | Patched homolog (Drosophila) | BG054916 | 10.34 | 2145.95 | 0.000007 |
230496_at | Hypothetical protein FLJ25477 | BE046923 | 10.34 | 131.12 | 0.000467 |
205372_at | pleiomorphic adenoma gene 1 | NM_002655 | 10.1 | 1069.14 | 0 |
229942_at | gb:AW024890/DB_XREF=gi:5878420/DB_XREF=wu92c11.x1 | AW024890 | 9.98 | 1649.01 | 0 |
214297_at | gb:BE857703/DB_XREF=gi:10371993/DB_XREF=7g46a02.x1 | BE857703 | 9.86 | 819.59 | 0.000003 |
229669_at | Hypothetical protein LOC339260 | AA166965 | 9.83 | 237.59 | 0.001318 |