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Table 3 Gene Transcripts significantly down-regulated in BCC compared to normal skin specimens (≥1.2 fold; ≥100; p < 0.05).

From: Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays

probe set

gene

Accession

fold change

Difference

P value

239929_at

hypothetical protein FLJ32569

AA918425

-28.24

-3433.29

0.014118

208962_s_at

fatty acid desaturase 1

BE540552

-20.2

-3188.7

0.045399

229476_s_at

thyroid hormone responsive (SPOT14 homolog, rat)

AW272342

-17.15

-4660.08

0.034919

207275_s_at

acyl-CoA synthetase long-chain family member 1

NM_001995

-15.11

-1865.7

0.039975

206799_at

secretoglobin, family 1D, member 2

NM_006551

-14.97

-1291.31

0.042413

234513_at

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like

AF292387

-13.28

-670.81

0.022544

221561_at

sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1

L21934

-12.23

-998.57

0.008422

206714_at

arachidonate 15-lipoxygenase, second type

NM_001141

-11.45

-3891.76

0.045644

214240_at

galanin

AL556409

-11.12

-1590.25

0.015802

244661_at

gb:AA946876/DB_XREF=gi:3110271/DB_XREF=oq53c11.s1/CLONE=

AA946876

-10.56

-399.74

0.017168

244780_at

sphingosine-1-phosphate phosphotase 2

AI800110

-9.79

-351.6

0.024348

201625_s_at

insulin induced gene 1

BE300521

-9.72

-1591.34

0.030044

231810_at

BRI3 binding protein

BG106919

-8.9

-877.2

0.021503

1565162_s_at

microsomal glutathione S-transferase 1

D16947

-8.6

-1071.37

0.030259

238121_at

Transcribed locus, weakly similar to XP_341569.1 similar to ORF4

AI473796

-8.29

-445.99

0.042733

211056_s_at

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta

BC006373

-7.88

-1432.56

0.032165

229957_at

Branched chain keto acid dehydrogenase E1, alpha polypeptide

BF446281

-7.63

-1214.3

0.025272

204675_at

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta

NM_001047

-7.35

-2832.7

0.027894

233030_at

adiponutrin

AK025665

-7.35

-1220.35

0.031698

231736_x_at

microsomal glutathione S-transferase 1

NM_020300

-7.28

-2497.22

0.031804

205029_s_at

fatty acid binding protein 7, brain

NM_001446

-7.24

-524.52

0.021739

201627_s_at

insulin induced gene 1

NM_005542

-7.23

-627.89

0.049971

209522_s_at

carnitine acetyltransferase

BC000723

-7.23

-2039.08

0.020824

226064_s_at

diacylglycerol O-acyltransferase homolog 2 (mouse)

AW469523

-7.1

-2291.54

0.032748

231156_at

gb:AW242782/DB_XREF=gi:6576459/DB_XREF=xm89g06.x1/CLONE

AW242782

-7.09

-339.26

0.045195

223184_s_at

1-acylglycerol-3-phosphate O-acyltransferase 3

BC004219

-7.01

-1374.94

0.045149

232428_at

monoacylglycerol O-acyltransferase 2

AK000245

-6.97

-182.68

0.038707

1558846_at

Pancreatic lipase-related protein 3

AL833418

-6.71

-2007.72

0.044402

205030_at

fatty acid binding protein 7, brain

NM_001446

-6.41

-1864.48

0.021392

205843_x_at

carnitine acetyltransferase

NM_000755

-6.41

-1166.98

0.020573

224435_at

chromosome 10 open reading frame 58///chromosome 10 open reading

BC005871

-6.37

-1905.14

0.007356

1560507_at

Diacylglycerol O-acyltransferase 2-like 3

BC039181

-6.28

-441.54

0.028259

215726_s_at

cytochrome b-5

M22976

-5.95

-3458.82

0.02416

220431_at

DESC1 protein

NM_014058

-5.94

-112.38

0.029175

225716_at

gb:AI357639/DB_XREF=gi:4109260/DB_XREF=qy15b05.x1/CLONE=

AI357639

-5.94

-1718.34

0.01598

204388_s_at

monoamine oxidase A

NM_000240

-5.89

-362.75

0.037779

45288_at

abhydrolase domain containing 6

AA209239

-5.83

-698.25

0.020361

218804_at

transmembrane protein 16A

NM_018043

-5.75

-234.79

0.045057

228479_at

gb:AI094180/DB_XREF=gi:3433156/DB_XREF=qa29b09.s1/CLONE=

AI094180

-5.7

-1191.04

0.029615

227804_at

hypothetical protein BC014072

BE328850

-5.62

-363.64

0.043913

234312_s_at

acetyl-Coenzyme A synthetase 2 (ADP forming)

AK000162

-5.54

-1297.68

0.044265

1562528_at

RAR-related orphan receptor A

BC040965

-5.48

-120.02

0.025055

208964_s_at

fatty acid desaturase 1

AL512760

-5.46

-3305.87

0.025757

213693_s_at

gb:AI610869/DB_XREF=gi:4620036/DB_XREF=tp21e08.x1/CLONE=

AI610869

-5.43

-1427.55

0.023253

237507_at

keratin 6 irs3

AI333069

-5.43

-271.6

0.008082

204389_at

monoamine oxidase A

NM_000240

-5.4

-180.28

0.0359

214598_at

claudin 8

AL049977

-5.27

-370.2

0.01827

201963_at

acyl-CoA synthetase long-chain family member 1

NM_021122

-5.19

-4459.79

0.010049

218434_s_at

acetoacetyl-CoA synthetase

NM_023928

-5.17

-1842.1

0.004574

221552_at

abhydrolase domain containing 6

BC001698

-5.06

-402.38

0.024809

  1. Top 50 transcripts – based on fold difference are shown (complete list is supplied as supplementary material).