Table 4 GOstat analysis of biological processes.
From: Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays
GO Number | Observed Transcripts | Total Transcripts | GO Category | P value |
|---|---|---|---|---|
GO:0019222 | 293 | 3309 | regulation of metabolism | 1.24E-33 |
GO:0006351 | 264 | 2884 | transcription, DNA-dependent | 5.41E-33 |
GO:0006355 | 258 | 2809 | regulation of transcription, DNA-dependent | 1.61E-32 |
GO:0006357 | 55 | 280 | regulation of transcription from RNA polymerase II promoter | 5.40E-31 |
GO:0008134 | 57 | 346 | transcription factor binding | 6.86E-24 |
GO:0016563 | 45 | 250 | transcriptional activator activity | 9.36E-22 |
GO:0003677 | 240 | 2906 | DNA binding | 1.54E-21 |
GO:0003712 | 44 | 276 | transcription cofactor activity | 3.54E-17 |
GO:0007049 | 89 | 807 | cell cycle | 9.89E-17 |
GO:0016043 | 163 | 1986 | cell organization and biogenesis | 8.78E-14 |
GO:0003713 | 30 | 171 | transcription coactivator activity | 1.08E-13 |
GO:0008283 | 65 | 560 | cell proliferation | 1.17E-13 |
GO:0051726 | 61 | 522 | regulation of cell cycle | 5.62E-13 |
GO:0000074 | 60 | 518 | regulation of progression through cell cycle | 1.51E-12 |
GO:0005578 | 48 | 377 | extracellular matrix | 3.00E-12 |
GO:0007155 | 77 | 874 | cell adhesion | 5.65E-08 |
GO:0008380 | 24 | 173 | RNA splicing | 3.60E-07 |
GO:0016477 | 18 | 112 | cell migration | 5.56E-07 |
GO:0016055 | 19 | 128 | Wnt receptor signaling pathway | 2.09E-06 |
GO:0008219 | 60 | 675 | cell death | 2.29E-06 |
GO:0007167 | 25 | 207 | enzyme linked receptor protein signaling pathway | 1.13E-05 |
GO:0030154 | 50 | 550 | cell differentiation | 1.13E-05 |
GO:0005604 | 13 | 62 | basement membrane | 7.37E-05 |
GO:0051301 | 22 | 190 | cell division | 0.000156 |
GO:0042981 | 38 | 418 | regulation of apoptosis | 0.000269 |
GO:0000904 | 11 | 66 | cellular morphogenesis during differentiation | 0.00262 |
GO:0043123 | 13 | 91 | positive regulation of I-kappaB kinase/NF-kappaB cascade | 0.00344 |
GO:0005581 | 11 | 73 | collagen | 0.00597 |
GO:0030198 | 8 | 43 | extracellular matrix organization and biogenesis | 0.00788 |
GO:0007154 | 247 | 4475 | cell communication | 0.0122 |
GO:0005583 | 4 | 11 | fibrillar collagen | 0.0125 |
GO:0008286 | 5 | 20 | insulin receptor signaling pathway | 0.0182 |
GO:0016049 | 17 | 174 | cell growth | 0.019 |
GO:0008361 | 17 | 174 | regulation of cell size | 0.019 |
GO:0005610 | 2 | 2 | laminin-5 | 0.0205 |
GO:0008083 | 20 | 221 | growth factor activity | 0.0232 |
GO:0005588 | 2 | 3 | collagen type V | 0.0477 |