Figure 4
From: Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest
Concentration-dependent effects of apigenin on the cell cycle. Higher concentrations of apigenin cause a concomitant increase in the percentage of cells in the G2/M phase. AsPC-1 [F (3,8) = 12.79, P < 0.002 (P < 0.01 with 100 μM)]; CD18 [F (3,8) = 9.504, P < 0.0128 (P < 0.05 with 50 μM and P < 0.01 with 100 μM)]; MIA PaCa2 [F (3,10) = 6.062, P < 0.0128(P < 0.01 with 100 μM)]; S2-013 [F (3,10) = 4.071, P < 0.0394 (P < 0.05 with 100 μM)]. *= P < 0.05; **= P < 0.01 compared with control.