Figure 5
From: Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest
Effects of apigenin on proteins involved in the G2/M cell cycle phase transition. Expression of both cyclin A and cyclin B were both decreased in apigenin-treated cells compared to controls. While the expression of the cdc2 protein was unchanged, levels of phosphorylated cdc2 were decreased in treated cells. Expression of cdc25A and cdc25C were also decreased in treated cells compared to controls.