Figure 7
From: MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo
Ad-mda7 activates the caspase cascade in vivo. Activation of procaspase-3, procaspase-9, and PARP expression was observed in both Ad-luc-treated- and Ad-mda7-treated tumor tissue lysates compared to PBS-treated tissue lysate. However, the activation of these molecular markers was higher in Ad-mda7-treated tumor lysates compared to Ad-luc-treated lysates. β-actin was used as a loading control.