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Table 1 Cell cycle distribution in ovarian cancer and normal cells treated with PBS, Ad-luc or Ad-mda7

From: MDA-7/IL-24 suppresses human ovarian carcinoma growth in vitro and in vivo

  MDAH 2774 (%) OVCA 420 (%) IOSE 80 (%)
  G1 S G2M G1 S G2M G1 S G2M
PBS 72.2 ± 10.5 20.4 ± 9.3 7.3 ± 1.5 68.2 ± 4.9 21.7 ± 5.2 10.0 ± 1.6 40.2 ± 1.4 42.0 ± 2.6 18.0 ± 1.6
Ad-Luc 52.5 ± 6.2 25.2 ± 3.0 22.2 ± 3.3 68.2 ± 6.3 13.1 ± 2.3 18.2 ± 4.6 55.3 ± 2.2 26.3 ± 1.2 19.0 ± 1.5
Ad-mda7 243 ± 38 27.0 ± 14.6 50.2 ± 16.4 57.0 ± 4.8 14.4 ± 2.4 29.0 ± 4.2 48.8 ± 3.6 28.6 ± 2.1 23.0 ± 2.5
  1. NOTE: Cells were treated with PBS, Ad-luc or Ad-mda7 for 72 hours followed by FACS analysis. The percentage of cells In each cell cycle phase was determined by analysis of the DMA content. Values are the means of duplicate experiments ± SD.