Table 1 Clinical, methylation and CGH data for prostate cancer tissues
Tumor No. | Stage | Gleason Score | Molecular Group | LINE-1 %hypo | No. hypem. genes | Chromosomal losses | Chromosomal gains |
|---|---|---|---|---|---|---|---|
36 | pT3bN0 | 7 | 1 | 4 | - | 3q21q26.2 | |
38 | pT2N0 | 7 | 4 | 4 | - | - | |
50 | pT3bN0 | 7 | hypo | 10 | 4 | 1q31 | 6p,7p,16p,17p, 18p,19, 20q13,21,22,Y |
65 | pT3bN0 | 7 | both | 9 | 4 | Y | 1p33p34.3, 2p21p23, 2q14.1q14.3, 2q33q36, 3p14.1p21.3, 3q25.1q26.3, 4q13.3q28, 5q22, 5q31.2q32, 6q16.1q22.1, 8q22.1q23, 10p11.2p13, 10q11.2q22.3, 12q13.2q24.31, 13q21.1q31, 14q21q32.2, 18q11.2q22, Xp21.3q27 |
83 | pT3bN0 | 7 | hypo | 6 | 4 | 1q31, 2q33q37, 4q31, 13q21q31, 15q24, | 4q12, 5q13, 17p, 18p, 19, Y |
89 | pT2bN0 | 3 | hypo | 5 | 2 | 9q33q34, X | 2q11q24, 4q12q22, 6q22, 12p,18p, Y |
93 | pT3bN0 | 7 | 4 | 4 | - | Yq | |
95 | pT3bN1 | 10 | hypo | 7 | 4 | Xq | 18p, Y |
99 | pT2bN0 | 5 | 0 | 1 | - | 2q14q24,10q11q21 | |
101 | pT3aN0 | 8 | none | 0 | 3 | 1p36, 14q31q32, 17p, 22 | - |
105 | pT3aN0 | 5 | 1 | 1 | 1p36,2,3,4 | - | |
107 | pT3aN0 | 7 | none | 3 | 4 | 18p, Y | 4q24, 6q22, Xp11.2p11.4 |
117 | pT3bN0 | 5 | 3 | 4 | - | 1q21q25,2q11q14,19q13 | |
119 | pT3bN1 | 9 | none | 1 | 3 | 7p15pter, 15q23qter, Y | 10q21q22 |
121 | pT2bN0 | 6 | chrom8 | 1 | 4 | 1q32q41, 3p21, 4p15p16, 8p22p23, 9p23p24,10q25q26, 11q23q25, 12q24, 13q32q34, 14q24q32, 15q24q26, 17q24q25, Xp21p22 | Yq |
123 | pT2aN0 | 5 | 1 | 1 | 9q21.2q21.3, 10q26, 16p, Y | 2p14p16, 2q24.3q32.1, 6q14q16.1 | |
125 | pT2bN0 | 6 | 1 | 0 | 14q31 | - | |
127 | pT2bN0 | 7 | none | 2 | 2 | 7q36, Yq | 2q22q32.3, 4q11q31.3, 13q14.1q21.1, 14q21q23, 15q21.1q23 |
133 | pT2bN1 | 7 | chrom8 | 0 | 4 | 22, Y | 1q, 2q22q34, 3q11.1q26.1, 4q22q27, 5q21q31, 6q21q24, 8q11q23, 10q11q21.3, 12q21q22, 14q12q22, X |
137 | pT2bN0 | 8 | chrom8 | 1 | 1 | 16, 17, 18p, 18q11.1q21.1, 19, 21q22, Y | 3q23q26.3, 4q13.2q21.3, 5q, 7q13q31, 8p21pter, 8q24, 9p, 14q13qter |
139 | pT3bN1 | 9 | chrom8 | 1 | 4 | 19q, Y | 1q25q31, 2q11q33, 3, 4q, 5q13q23, 6q14q25, 7q21qter, 8q13q23, 11q14qter, 13q21q32, 14q11.1q21, 18q12, Xq21.3qter |
141 | pT2bN0 | 4 | chrom8 | 0 | 2 | 16, 17, 18p, 19, 20, 22, Y | 1q31q32.1, 2, 3q13.3qter, 4q11q31.1, 5q14qter, 6q, 7p12pter, 7q22q31.2, 8q12q21.2, 10q21.1q23.1, 11q14.3qter, 12q14qter, 13q14.1qter |
145 | pT4N1 | 7 | hypo | 11 | 3 | Y | 3q25q27,4q24q26,7q11q22,13q31q34,17p,18p |
149 | pT2bN0 | 6 | 2 | 2 | Y | 2p, 4p12, 4q24q26, 5q11q13, 7p12, 8q23q24, 9,11q22, 12q12q15, 14q24, 17, 19, 20q13, | |
151 | pT3aN0 | 7 | 0 | 1 | 3p13p14 | 6p14, Xp21 | |
153 | pT3aN0 | 5 | 2 | 1 | Xq11.2q13 | ||
155 | pT3aN0 | 5 | 5 | 4 | 19p | 3p25p26, Y | |
157 | pT2aN0 | 8 | 2 | 0 | - | 1q21q31, 2q12q24, 3q, 4q12q21, 5q13q14, 6q14q16, 7q11, 8q12q22, 12q12q13, 18p, Y | |
161 | pT2bN0 | 5 | 3 | 4 | 15q22q24, Xq22q25 | - | |
163 | pT3bN1 | 5 | chrom8 | 2 | 2 | 16, 17p, 18p, 20, Y | 1q25qter, 2p11p16, 2q32q34, 3q12, 3q21q27, 4q, 6q15q24, 8q12q21, 8q23q24, 12q13q21, 13q14q32, 14q12q21, 18q, Xq11.1q26 |
169 | pT3aN0 | 7 | chrom8 | 3 | 2 | 16, 17p, 18p, 19, Y | 2, 3, 4q, 5q, 7p15pter, 8q22q24, 13q31qter, 14q24qter, 17q23, 18q21qter, Xq21.3q26 |
171 | pT2bN0 | 5 | hypo | 8 | 4 | 10q26, 18p. -19, 22, Y | 1p31, 2p12p13, 2q11q34, 4q22q26, 5q22, 6q11q23, 14q22q24, X |
175 | pT2bN0 | 8 | 11 | 4 | 13q14 | - | |
183 | pT3aN0 | 6 | 19 | 4 | 1p36,9q34 | - | |
187 | pT2bN0 | 8 | chrom8 | 1 | 3 | 16, 17p, 18p, 19, 21, 22, Y | 1, 2, 3q13qter, 4q, 5q14q33.1, 6q16q23, 7p, 7q22q33, 8q, 11q14.3qter, 12q14qter, 13q21qter, 14q24q31, 15q, Xq22qter |
189 | pT2bN0 | 7 | none | 0 | 4 | 3p25p26, 10q26, Xq22qter, Yq | - |
191 | pT2bN0 | 7 | 0 | 3 | 4q31, 5q31q35, 9q33, 12p12 | - | |
205 | pT3aN0 | 7 | 5 | 1 | 18p, 19, 22, Y | 2q31q33, 6q22.3q23, 10q21q22, Xp11.1p11.4, Xq | |
209 | pT3aN0 | 7 | both | 8 | 4 | 1p36, 8p, 16, 17, 18p, 19, 20, 22, Y | 1q31q32.1, 2q11.1q34, 3, 4q21.1qter, 5q14q31, 6q11q23, 7q21q34, 8q, 9, 11q14q22, 12q15q24, 13q14qter, 18q |
213 | pT2aN0 | 7 | 8 | 4 | 8q24.2qter, 14q32, 16, 17, 18p, 22, Y | - | |
215 | pT3aN0 | 7 | 9 | 4 | 19q13, 22q13,Y | 3q24q26, 5q12, 8p12, 17, 18, Xp11p21, X21q24 | |
217 | pT2bN0 | 8 | 5 | 4 | 18p13, Y | 2q33q35, 4q13q28,5q21q31,8q21,8q24,12q13, 12q21q23, Xq13q25 | |
219 | pT4N1 | 7 | both | 21 | 4 | 5q34qter, 8p22pter, 19, Yq | 1p22p31.3, 4q21q22, 4q31.1, 5q13, 6q24q26, 7q, 8q21q24, 10q21, 11q14q22, 20q13, Xq13q22 |
225 | pT3bN0 | 6 | 4 | 4 | 4q28, 8q24qter, Yq | - | |
227 | pT2aN1 | 7 | 3 | 4 | 22q13 | 3q11q21 | |
232 | pT2bN1 | 7 | both | 13 | 4 | 8p22pter | - |
245 | pT3aN0 | 7 | 4 | 3 | 17p13, 18p | 1p31 | |
247 | pT3bN1 | 7 | chrom8 | 3 | 3 | 8p21pter, 9q21, 22, Y | Xq12 |
253 | pT3aN1 | 7 | 1 | 4 | 1p36, 2q33q37, 6p21.3p25, 8p21, 14q31q32, Y | - | |
256 | pT3bN0 | 7 | 1 | 4 | 2p2p21, 6q, 15q26,16p, 18,X | - |